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The level of stress-related pathology varies from one person to another, due to the differences in the levels of immune and inflammatory response specifically mast cell response to various stressors and activation signals (Forsythe and Ennis, 2000

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Graphical Abstract Keywords Acetaminophen, Caspase-1, Drug-induced liver injury, Inflammasome, NOD-, LRR-, and pyrin domain-containing 3, NLRP3 Introduction Acetaminophen (APAP), commonly known as paracetamol, is a widely used over-the-counter medication renowned for its analgesic and antipyretic properties

For each acylcarnitine molecule traversing the inner mitochondrial membrane, a molecule of carnitine is shuttles out