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attached proteolysis-targeting chimeras (PROTACs) to lactam cyclic peptide as ER-binding ligand, 6-aminocaproic acid as a linker, and a hydroxylated structure for recruiting E3 ligase known as 16 compound

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3.2.2 Regulation of hepatic lipid metabolism Dual GLP-1 receptor agonists facilitate hepatic lipid metabolism through coordinated activation of intracellular signaling pathways that suppress lipogenesis and enhance fatty acid oxidation