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officinarum was shown to possess an anti-inflammatory effect in LPS-activated mouse RAW 264.7 macrophages and human PBMCs in vitro (Yadav et al., 2003) HMP at the concentration range of 6.2525 M significantly reduced the NO level in the mice macrophages and IL-1 and TNF- levels in PBMCs in a dose-dependent pattern

Informal tracking with scattered notes or photos fragments the record and hides patterns during dose increases, making it harder to connect recurring reactions that worsen after two days to specific sites or dose changes