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1 While GIP is an incretin hormone that enhances mealstimulated insulin secretion and modulates glucagon secretion in a glucosedependent manner to support postprandial lipid clearance and regulate food intake, 32 , 33 , 34 glucagon increases hepatic glucose output and has been shown to delay gastrointestinal transit, stimulate insulin secretion in certain circumstances, and reduce appetite and body weight

Eat smaller meals every 3-4 hours rather than three large meals daily

He stopped taking the drug after a few months

Most patients report appetite changes within one week, though the scale may not shift until week two or three of consistent dosing