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In: Howard R, Kullmann D, Werring D, Zandi M (eds) Neurology: A Queen Square Textbook, 3rd edn

However, by increasing SIRT1 accumulation in the ovary, SP and L-car could attenuate DOX-induced mtDNA damage in ovarian cells, subsequent mitochondrial dysfunction, and resulting apoptosis in preantral follicles, which was consistent with the earlier observation 92