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To generate reducing equivalents, in the form of NADPH, for reductive biosynthesis reactions within cells
The targeted reactivation of p53 distinguishes this peptide from systemic cytotoxic strategies
On the other hand, the invoked cell death and intracellular stress responses can regulate the upstream regulators and downstream effectors of cGAS-STING, affecting immune responses and pathogen clearance
benefits for neuropathy were present but less pronounced than for retinopathy or nephropathy, reflecting the slower reversibility and multifactorial nature of DPN [61]
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