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The main symptoms of Fabry disease are diverse and include angiokeratomas, sweating abnormalities (hyper- or hypohidrosis, anhidrosis), lymphedema [7], acroparesthesias, hearing loss, tinnitus, proteinuria, renal failure, arrhythmias, angina, left ventricular hypertrophy, strokes, abdominal pain and diarrhoea[5, 8] (Fig

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