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Description

SAM allosterically activates mammalian CBS 2.5-5 fold (Janosik et al., 12 deficiency, methionine block implies that SAM (driven by Met) is lowered as well and hence it is plausible CBS is less effective

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A small ( n = 10) open label study demonstrated that an 8-week sulforaphane intervention improved cognitive function in a cohort of participants with schizophrenia (Shiina et al., 2015)

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