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e.g., angiotensin-converting enzyme inhibitor(s) [ACEi], or angiotensin receptor blockers [ARB]), currently available treatments include sodium-glucose cotransporter 2 inhibitors (SGLT2i), glucagon-like peptide-1 receptor agonists (GLP-1 RA), and nonsteroidal mineralocorticoid receptor antagonists (ns-MRA), such as finerenone [5,6,7,8]

Gupta AK, Renaud HJ, Wang T, Cooper EA, Mann A, Polla Ravi S

As potential executing metabolites of the enhanced cytotoxic potential we identified oxidized polyunsaturated fatty acids, such as 13-HODE, in supernatants of albumin-treated C

These authors also established that the combination of APR-246 with different compounds and strategies inducing ferroptosis (pharmacological compounds, or genetic inactivation of SLC7A11 or GPX4) had a synergistic effect on the promotion of AML cell death, both in vitro and in vivo