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Individuals with a BMI of 27 or greater who have at least one weight-related health condition, such as high blood pressure or high cholesterol

Common side effects (usually when starting or increasing the dose): Nausea, vomiting, diarrhea, constipation Abdominal pain or discomfort Reduced appetite (helpful for weight loss but can feel uncomfortable) These occur because the medication slows gastric emptying, making you feel full faster

Subjects were propensity-score matched 1:1 based on age, sex, and index date

Muscle mass and glucagon-like peptide-1 receptor agonists: adaptive or maladaptive response to weight loss