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Although treatment with each of the three compounds alone was also effective, the combination of chlorogenic acid (CA), neochlorogenic acid (NCA), and cryptochlorogenic acid (CCA) demonstrated the greatest effect on HCECs in the scratch wound-healing assay
Fractional inhibitory concentration index (FICI) analysis: FICI was used to calculate synergism, indifference, or antagonism between two compounds according to the following equation: "CA" refers to the MIC value of drug A in combination with drug B, where "MICA" refers to the MIC of drug A alone
doi: 10.3389/fphar.2022.969107 Received 14 June 2022 Accepted 12 September 2022 Published 03 October 2022 Volume 13 - 2022 Edited by Dan-Qian Chen, Northwest University, China Updates Copyright 2022 Chen, Ye, Wang, Liu, Wang, Wang, Xu and Gong
