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In parallel, the liver-expressed enzyme tryptophan 2,3-dioxygenase (TDO2) catalyzes the same initial step of tryptophan catabolism under homeostatic conditions and is primarily regulated by glucocorticoids and tryptophan levels 43,51

Improved sleep architecture can boost overall health, including better cognitive function and physical recovery

UPF are high in saturated and trans fats, which stimulate a greater reward than foods containing natural fats (137)

826 Downregulation of Panx1 significantly reduces ferroptosis and iron accumulation in renal cells induced by erastin, through inducing HO-1 expression and the mitogen-activated protein kinase (MAPK)/ERK pathway