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Ju HY, Song SE, Shin SK et al (2025) Fulvic acid inhibits the differentiation of 3T3-L1 adipocytes by activating the Ca2+/CaMK/AMPK pathway

In BV2 microglial cell lines subjected to lipopolysaccharide (LPS)-induced neuroinflammation, both lactylation-mediated inhibition of p53 activity and direct knockdown of p53 protein can disrupt the control of the NF-B inflammatory signaling pathway, ultimately leading to abnormal expression of pro-inflammatory factors and M1 polarization of microglia [132]

In conclusion, although many reports previously evidenced the regulation of signaling pathways by GSTs in various in vitro cell systems, we demonstrate for the first time that the invalidation of Gstp1/p2 affects multiple key events of the hepatocyte cell cycle in vivo after PH

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