People who use folate supplements may also consider ensuring adequate vitamin B12 intake, particularly if they are older adults, vegetarians, vegans, or have absorption concerns
Additionally, by inhibiting HMG-CoA reductase (an enzyme not only required for the production of cholesterol, but other metabolites as well), statins may reduce levels of the critically important antioxidant molecule CoQ10
In heterodimeric GST complexes such as those formed by the cytosolic mu and alpha classes, however, the cleft between the two subunits is home to an additional high-affinity nonsubstrate xenobiotic binding site, which may account for the enzymes' ability to form heterodimers
Neuroendocrinology Letters, 2011, PMID: 11335874) Results of 12-months treatment with Epithalon in patients with signs of accelerated aging showed normalizing effect on metabolism and condition of various functional systems