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Benefits: Improves the appearance of even skin tone and texture Glutathione and PEPHA-TIGHT work together to support skin structure, reducing the appearance of fine lines and wrink

Shyamali Dharmage who provided guidance for interpretation of the included studies and provided comments on the manuscript

This improvement happens partly through weight loss itselfevery kilogram lost reduces insulin resistancebut also through direct GLP-1 receptor signaling on pancreatic beta cells, which become more precise at matching insulin output to actual blood glucose needs

However, there is only limited indirect evidence on the possible interaction of incretin hormones and GH secretion