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The aim of the current study was to review the role of GPX3 in OC and investigate the potential factors and effects of GPX3 on OC stem cells (OCSCs)

Abstract Hypertension is one of the major risk factors for cardiovascular diseases and the main reason for premature death in older adults

Specifically, rutin can significantly upregulate the expression of ferritin heavy chain (FTH) and glutathione peroxidase 4 (GPX4), and downregulate the expression of acylCoA synthetase long-chain family member 4 (ACSL4), thereby inhibiting iron-dependent lipid peroxidation

These findings provide solid evidence that PS-MPs induce depression-like behavior in zebrafish through mechanisms involving neuroinflammation, circadian rhythm disruption, and neurotransmitter imbalances, and stressing the potential ecological risks of PS-MPs and contributing to our understanding of the neurotoxicity of microplastics