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Clinical research has shown substantial weight loss outcomes in study settings, with some participants experiencing significant reductions in body weight over time

Meglitinides, glitazones and alpha-glucosidase inhibitors were subsequently developed, but the five mentioned groups of oral antihyperglycemic agents are associated with variable degrees of undesirable or even severe cardiovascular events

Other Weight Management Medications in Obese and Overweight Patients

J Child Adolesc Psychopharmacol 17:791802 American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, 4th edn, text revision (DSMIV- TR)