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The TPH1 gene encodes the predominant tryptophan hydroxylase responsible for serotonin synthesis in enterochromaffin cells of the intestines

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At the population level, wanting is typically expressed as cue-reactivity to food and habitual craving tendency, with inter-individual variation associated with the responsiveness of reward-related brain regions (27)

The drug manufacturers have agreed to reduce the price to approximately $250 over the next two years