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Microtubules are polarized filaments: their minus ends associate with centrosomes and spindle poles, and their plus ends exhibit dynamic growth and instability [4, 5], but can be stabilized by interactions with cellular structures including the cell cortex [4, 11]

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Professional oversight and safety: Microneedling should be performed with the right protocols, sterile technique, and thoughtful screening, especially if youre prone to irritation or hyperpigmentation