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The FDA has described categories for bulk substances used in compounding and has highlighted safety concerns for certain substances

Exp Ther Med (2016) 12(5):288592

Other at-risk populations include individuals on chronic steroids, which cause muscle wasting, patients unable to engage in strength and resistance training, or patients with muscle-wasting conditions like chronic kidney disease. McGowan also noted that even healthy individuals should expect some muscle loss

These medications are typically prescribed when lifestyle modifications and oral diabetes medications have not achieved adequate glycaemic control, or as part of a comprehensive weight management programme for eligible patients