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Shortage or excess of dopamine can prevent proper function and signaling of these receptors, leading to disease states [158]

doi: 10.1186/s10194-019-0993-0 2

This phenomenon, called aerobic glycolysis or the Warburg effect, has been exploited for visualizing tumors in the clinical setting by imaging their uptake of the radiolabeled glucose analog, [18F] fluoro-2-deoxyglucose (FDG), via Positron Emission Tomography (PET)

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