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Several factors play a role, including: Starting Weight People with more weight to lose often see larger total losses

Gastrointestinal Adverse Reactions In clinical trials in adults for weight reduction, 73% of WEGOVY-treated patients and 47% of patients receiving placebo reported gastrointestinal adverse reactions, including severe reactions that were reported more frequently among patients receiving WEGOVY (4.1%) than placebo (0.9%)

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