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Most common (especially in first 4-8 weeks): Nausea Early fullness/satiety Constipation Mild reflux or burping Less common but important: Severe nausea preventing adequate eating or drinking Gallbladder issues (rapid weight loss increases gallstone risk) Pancreatitis (rare, more common with high triglycerides or gallstone history) Dehydration The side effect no one mentions: Undereating

Metformin in Patients With Type 2 Diabetes and Kidney Disease: A Systematic Review

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HDAC inhibition synergizes with ALK inhibitors to overcome resistance in a novel ALK mutated lung adenocarcinoma model