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Do higher doses worsen side effects

This resistance, researchers write, likely stems from concerns regarding high annual costs and the lack of immediate ROI. About 60% of survey respondents are not considering changes to their GLP-1 coverage in the near term, researchers say, suggesting these organizations are either satisfied with their current restrictive posture or are being intentional about changing plans until more data emerges about both costs and health outcomes

Harvard Women's Health Watch

True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant)