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It was initially developed to speed up the recovery of gastrointestinal function in patients after bowel surgery

The patient information leaflets for drugs such as Wegovy, Ozempic, and Mounjaro state that pancreatitis is an uncommon side effect, affecting about one in 100 patients

A significant influx of undigested proteins into the distal intestine as a result of impaired protein absorption encourages the overgrowth of proteolytic bacteria (Sorensen, 1965), which in turn causes an increase in protein fermentation clinically manifesting in protein-energy wasting, cardiovascular diseases, neurological syndromes, and CKD progression (Figure 3)

Vitamin B12 can be given in the subcutaneous tissue or intramuscularly