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For patients with a personal history of any cancer, even if treated, resolved and with all signs removed, this is generally an area of discussion that is longer and frequently requires an oncology clearance beforehand

For example, it can regulate pyruvate dehydrogenase (PDH) activity, promoting the conversion of pyruvate into the citric acid cycle and increasing energy production

and (iii) stimulation of adrenal androgen production (e.g., androstenedione and DHEAS), further augmenting the systemic androgen load (13, 61)

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