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Many different types of graft materials can be used, including grafts from inside the mouth, porcine small intestine, or bovine pericardium
Angiogenic signaling is a recurring theme in this area because vascular development plays an essential role in delivering oxygen, nutrients, and osteogenic precursor cells to healing bone tissue
It is studied through vascular marker response, VEGF related signalling, nitric oxide pathway interaction, tendon fibroblast behaviour, collagen matrix organisation and inflammatory marker changes
Surgical Technique: The size of the opening created for the stoma and whether it passes through the rectus abdominis muscle can impact hernia risk
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