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Following high-profile reports in 2024 of an elevated risk of nonarteritic anterior ischemic optic neuropathy (NAION) in type 2 diabetes patients taking glucagonlike peptide-1 (GLP-1) receptor agonists seen at one facility (Massachusetts Eye and Ear), there remains a need to clarify the potential risk of ophthalmic complications from semaglutide exposure using multicenter data

This medication works by mimicking the action of endogenous GLP-1, a hormone that stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways

It is important to note that sweating is typically a secondary effect related to other factors rather than a direct effect of GLP-1 medications themselves

McLaren At Skin Secrets by Dr