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The FDA-approved versions of these medicines - branded as Ozempic and Wegovy for semaglutide, and Mounjaro and Zepbound for tirzepatide - have undergone FDA review for safety and effectiveness in their approved forms and doses

On the other hand, cortisol deficiency slows down the metabolism causing fatigue, sluggishness, weight loss, and no desire of physical work

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I agree that insulin resistance remains the root driver behind obesity and type 2 diabetes, but its a challenging concept for most people and often oversimplified in public health messaging