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Because of this, drug companies often exclude breastfeeding people from clinical trials

In addition, several agents are in mid- or late-stage development for chronic diseases such as peripheral artery disease and atherosclerotic heart disease, which disproportionately affect individuals with SMIs

In addition, weight loss is a consistent finding in clinical trials investigating GLP-1RAs ( Reduction of hepatic and adipose tissue insulin resistance An improved insulin sensitivity is expected after chronic treatment with GLP-RAs mainly due to marked bodyweight reductions

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