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To make fair comparisons, cannabis users were matched with more than 4 million people who had no history of substance use or major chronic health conditions

In particular, since CB1Rs, the main target for the rewarding effects of cannabis, are expressed on incretin-secreting cells in rodents and may play a role in regulating GLP-1 secretion [58, 59]

Sleep disruption during early titration (from nausea or reflux) can impair growth hormone release and overnight recovery processes

For adults with type 2 diabetes and a high risk of heart issues, this medication has been shown to lower the risk of major cardiovascular events like heart attacks and strokes