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Singh et al, 2021), Genes common among published target sets include those related to redox biology (i.e., GCLC , SLC7A11 , TXN ) and the pentose-phosphate pathway (PPP, i.e., PGD , TALDO1 ), in addition to many NADP-dependent metabolic enzymes (i.e., AKR1C1 , AKR1B10 , and CYP4F11 )

We are all exposed to toxins in our environment such as car exhaust, charred foods, pesticides, cleaning chemicals, radiation from the sun, and trace amounts of heavy metals in our food

Ramachandran A, Jaeschke H