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Clinical Evidence on Semaglutide Weight Loss Effectiveness Major clinical trials demonstrate that semaglutide injection reduces body weight by an average of 9-15% compared to placebo in patients with overweight or obesity

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[DOI] [PubMed] [Google Scholar] 49.Davies M.J., Bergenstal R., Bode B., Kushner R.F., Lewin A., Skjth T.V., Andreasen A.H., Jensen C.B., DeFronzo R.A., NN8022-1922 Study Group Efficacy of Liraglutide for Weight Loss among Patients with Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial