I very much relate, all sorts of headaches, tension, migraine, some, I think, teeth related headaches, some eye-related - I think a lot of mine are hormone or stress related
If your peptide is loaded with histidine residues, it's going to be very sensitive to pH changes
Additionally, BPC 157 is present in most tissues (Seiwerth et al., 2018), where it can bind reactive free radicals and inactivate them at crucial positions not reachable by other antioxidants (Sikiric et al., 1993
Appetite Effects The question about appetite is interesting because the proposed mechanism could reasonably go either direction: Reduced lipogenesis and improved metabolic flexibility could produce secondary effects on appetite regulation NAD+ restoration has complex effects on hypothalamic appetite signaling Preclinical data do not consistently describe dramatic appetite changes In human use were it to become clinically available patient-reported appetite effects would be a relevant monitoring parameter, but the data do not currently support a strong a priori expectation