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A population PK model using data from 21 pediatric patients ages from birth to 17 years supported with extracorporeal membrane oxygenation (ECMO), and 19 pediatric non-ECMO patients ages from birth to 2 years found that clearance was related to serum creatinine while a higher volume of distribution was related to presence of ECMO support

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Similar content being viewed by others Introduction It is increasingly recognized that not only age but also the denaturalization of our food, lifestyle and environment are partly responsible for the current rise in non-communicable diseases such as obesity, type II diabetes mellitus (T2D) and related types of cancer