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Be cautious with: Crash diets and very low-calorie plans Aggressive fasting if you are not supervised Highly restrictive plans that cut major food groups without a medical reason If you have diabetes, kidney disease, or take insulin/sulfonylureas, get clinician input before big changes

This personalized insight helps you and your provider understand whether your body responds optimally to semaglutide alone or whether additional compounds or lifestyle modifications suit your genetic profile