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One According to a The 2016 review mentioned earlier reported several other findings: Rodent studies have shown that an olive oil-enriched diet increased GLP-1 secretion, glucose-stimulated insulin secretion, and glucose tolerance

A reviewer suggested we perform a GWAS for each medication class separately to avoid masking signals, given that tirzepatide targets both GLP-1 and GIP receptors

Glucose-dependent insulinotropic polypeptide (GIP) receptor deletion leads to reduced bone strength and quality

The N-terminal region of GLP-1 is considered critical for receptor activation, whereas the C-terminal region predominantly facilitates receptor binding