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In adults and older children, the total volume used should also stay within safe limits animal studies suggest up to about 30 mL (the full vial) can be given to an adult without benzyl-alcohol toxicity, but one should still use only the amount needed and discard the rest if sterility is lost

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Fertilizers and other affordable chemicals have been used to successfully replace the compounds in Zarrouk medium, in which ammonium nitrate proved to be a highly effective nitrogen source (Kumaresan et al