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Both, cuproptosis and disulfidoptosis, utilize redox imbalance, and agents targeting intracellular redox homeostasis may activate multiple pathways of cell death to better inhibit tumor progression (141)

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The rationale underlying the analysis implies that an individual experiencing efficacy and tolerability of a treatment is unlikely to change to another treatment

The goal is to decrease estradiol levels to levels within the normal male range and reduce associated symptoms of elevated estrogen (hot flashes, night sweats, irritability/mood lability, poor sleep, bloating/water retention, erection changes, or midsection weight gain)