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Some 95% of clinicians express some concerns about patient use of peptides even if broader access expands, primarily citing self-treatment without medical oversight (33%) and side effects and safety risks (30%), according to a May Sermo survey

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5 In addition to the potential benefits of GLP-1 receptor agonists already mentioned, several dedicated cardiovascular outcome trials have reported positive cardiovascular and kidney outcomes with agents from the GLP-1 receptor agonist class