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13 ClinicalTrials.govTrial registry searches for IGF-1 analogs

It depends on both copper and zinc as cofactors, but only copper regulates its activity ( 2 O 2 , CuZn-SODs activity is suppressed, via oxidation of His-118 to form 2-oxo-histidine ( Cytochrome c oxidase, also known as complex IV, at a final step in the respiratory chain, catalyzes the reduction of oxygen to water