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Try to drink at least 8 oz of water per hour while you are awake

Based on Phase 2 safety data (Jastreboff et al., NEJM 2023), common early adverse effects reported include: Nausea (the most frequently reported adverse effect) Vomiting Diarrhoea or constipation Reduced appetite Mild fatigue or dizziness These effects are consistent with the GLP-1 receptor agonist class and typically reflect the gut's adaptation to altered gastric emptying and hormonal signalling

Safety and Side Effects The trial noted a slightly higher discontinuation rate due to gastrointestinal side effects with the 7.2mg dose (3.3%) compared to the 2.4mg dose (2%)

For example, rotating injection sites, cleaning the skin properly, and avoiding injections in areas that are irritated or scarred can reduce the risk of redness or rash