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We find that this treatment offers powerful support for patients experiencing various symptoms related to suboptimal B12 levels

In parallel, excessive Cu + generated in GSH-rich reductive environments can bind lipoylated mitochondrial TCA-cycle proteins such as DLAT, inducing aberrant protein aggregation and triggering cuproptosis across multiple cancer types 187,189,192-194

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These findings collectively demonstrate that FOXO4-DRI alleviates OGD-induced endothelial cell senescence and restores functional damage caused by OGD