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Eid, R., Arab, N.T.T., Greenwood, M.T

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Structure-Activity Relationship Data , Four decades of Dermorphin SAR research has generated extensive structure-activity data across systematic sequence modifications and identifying the key pharmacophoric elements required for MOR binding and selectivity, the structural tolerance for modification at each position, and how changes to the D-Ala residue, C-terminal amide, and individual side chains affect receptor affinity, selectivity, and agonist efficacy

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