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A Phase 3 trial reported an average of 28.7% body weight loss (roughly 71 pounds) in 68 weeks

First, confirm it is a true plateau, at least three weeks of no downward trend in the weekly average, rather than normal fluctuation

Upon binding, it may influence signaling pathways associated with: Growth hormone release patterns Endocrine system regulation Peptide stability and circulation time The DAC modification is specifically examined for its potential to extend peptide activity by binding to plasma proteins, thereby allowing prolonged exposure in experimental models