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The piriform cortex comprises heterogeneous populations of excitatory and inhibitory neurons

Glucagon directly stimulates hepatic fat oxidation, essentially instructing the liver to burn its stored fat for fuel

PAE is a well-established, minimally invasive procedure performed using image guidance to improve precision and reduce risks

Its binding to VMAT2 is very strong, making it's effect appear irreversible, with trace amounts of the drug remaining bound to vesicular membranes for many days, and its clinical effects lasting many days to weeks, and may persist until new transporter proteins are synthesized (German et al, 2015