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A meta-analysis of four observational studies, following a total of 7,475 older individuals for 3 to 16 years, found a weak association between an elevation in vitamin B 12 of 50 pmol/L in blood and a reduction in fracture risk (114)

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(2015) demonstrated that patients with large-artery atherosclerotic ischemic stroke and transient ischemic attack (TIA) exhibited significant gut dysbiosis, characterized by increased opportunistic pathogens (e.g., Enterobacter, Megasphaera, Desulfovibrio ) and reduced beneficial genera like Bacteroides and Faecalibacterium

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