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Researchers concluded that semaglutide was associated with a 15% reduction in fracture incidence. The full research has not been published yet, so the full limitations are not clear at this time

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The availability of the amino acid sequences of GLP-1 and GLP-2 obtained from the decoding of the nucleotide sequences based on the genetic code allowed for the chemical synthesis of the predicted peptides, examination of their biological activities, and preparation of peptide-specific antisera