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Genetic factors may play a role in treatment response, though it's important to note that pharmacogenomic testing is not currently recommended for clinical decision-making regarding these medications

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Enzyme activities were moderately to highly correlated with TPC and TFC in the following order: SOD (r=0.976 and 0.969), GPX (r=0.904 and 0.928), PPO (r=0.830 and 0.821), and CAT (r=0.498 and 0.588)

Yes, the glutathione from the suppository can be absorbed into the systemic circulation and thus have effects throughout the body, although the primary intention may be localized treatment