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Notably, inhibition of MAPK/ERK signalling exacerbates 3-HK-induced mitochondrial dysfunction and cell death, implicating impaired cellular resilience pathways in amplifying KYN-mediated toxicity

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Quick Answer: GLP-1 medications do not directly alter taste bud structure but can significantly change taste perception through effects on brain reward pathways, delayed gastric emptying, and gastrointestinal symptoms